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Jordan St Angelo May 2011
This is an ode to Adderall,

that wonderful mixture of

dextroamphetamine sulfate

dextroamphetamine saccharate

amphetamine

aspartate monohydrate

and amphetamine sulfate capsules

that all combine together

to form a prescribable pill

questionably similar to the Schedule II controlled substance street drug

commonly refered to as "Speed."


This is an ode to the children

who are bundles of energy caged in a classroom

incapable of concentrating

on the miniscule tasks given to them

by pedagogical authorities that

promise societal success and economic happiness

to those who complete their work on time

without a fuss or a doubt as to why they're

filling in bubbles on paper in the first place.

The confused children who watch

as others with calmer brains

fixate eyes on textbooks

rather than out the window.


This is an ode to Society

deeming these individuals as broken

choosing to wound then medicate

rather than proliferate.

That took their inquisitiveness

and locked it in a book with the label "DISORDER"

stating that you will never be anything

unless you think and feel the same way we do.

And much like a mad doctor

lobotomizing those whom he thinks insane

they synthesized a pill

to dampen a torrential brilliance

allowing them to place their sedated children

back in the box where they belonged.


This is an ode to the college students

chained by academic standards

expected to excel towards great things

if only they reach that ethereal diploma.

The students who crave the artificial focus

the increased capacity for concentration

with the broadened spectrum of perception

the sense of purpose in the tedium

the ungodly ability to think clearly

and perform the meaningless tasks they expect of us.

The students who go through illegal means

to purchase said drug

to swallow or snort

and dive back into the mountain of responsibility

with a new found sense of productivity and motivation.

An ode to the students

unable to find purpose in studenthood

the ones who find more virtue in watching the sunset

burn clouds into firework oblivion

before then blessing us with uncritical night.

An ode to the students

who discover more education

in climbing to the top of a mountain

and yelling a nonsense decree of passion

just to watch the echo

bounce from shore to shore

in cathartic reverberation.

The ones

for which our pill

is the only possible manner

of assigning purpose to purposeless assignments.

These are the ones

who must binge

cram for days before

the big exams

going whole nights without sleep

or food.

The ones slowly cracking under the increasing pressure of academia

spending more time questioning why they must complete their homework

instead of actually completing it.


This is an ode to my brothers and sisters

who stand in horror at the mold we must fit into

crafted by an unknown unshakable entity.

The ones who lost the appeal of cookie-cutter success

in exchange for a small understanding

of the way things really work.

The cogs that twisted off the machine

and now sit lotus-posed in the corner.

My fellow birds with broken wings

still expected to fly.

My fellow carpenters expected to build their estates

yet not given the proper tools to do so.

The ones of cursed cold clarities

perfectly capable of clutching

those fifteen minutes of dynasty

yet refrain from doing so due to

the immaculate futility of it all.


This is an ode to a drug induced rant

that no one will read

the one that I chose to write

instead of doing my **** homework in the library

like a compliant student.


This is an ode to the pressure-oriented procrastinators

that delay and yet again delay

their petty necessary obligations due to purposeless and exhausted motivation.

Swallowing substances to summon some sort of incentive

to fill in the bubbles

and cater to the Society they find so confusing

the ones who only under influence of synthesized chemicals

find reason to squeeze into that culturebox

that cascades down a bumpy man-made conveyor belt

branding a diploma onto your forehead

injecting an occupation into your veins

transforming your pupils to dollar bill signs

demanding you breed children

to do the same as you have

and you'll never be happy unless you do these things

right?


This is an ode to those who reside in the shadows

of our broken social system

and conjure up great conversations

pertaining to everything and nothing

that are as wonderful and necessary

as the prints of your fingers

caressing down a comfortable torso

just before the sun rises

the untouchable indescribable realizations of life and love

that are completely irrelevant in their eyes

but are entirely necessary for our survival.


This is an ode to the overwhelming feeling of love

greatly exacerbated by a pharmaceutical delight

whereupon connections with other humans

become both incredibly appealing and oddly magnetic

for a few electric hours.

The oxygenating satisfaction felt

the instance just after the small talk architecture masks

fall to the floor

and right before we put them back on.


This is an ode to the minutes before the amphetamine crash

where the world still doesn't make sense

but we briefly don't mind

because a few fleeting moments of energy and purpose

in this otherwise detestable confine of reality

are all you can really ask for

as you complete the assignments

then step outside

to smoke yet another cigarette (they're absolutely wonderful on Adderall try it some time it'll **** you slowly but then again what won't?)

only to witness our Sun

breeding fire clouds in the east

illuminating the Western Abyss into purple-gold spectral oblivion

and in consequence therefore

between puffs of a necessary cigarette

you grin to yourself in quiet victory.


This is an ode to misaligned priorities

to those who when walking to everimportant final examinations

think not of the curriculum beaten into their skulls

but take careful measure to step on every crack on the sidewalk

who stare not towards the future

but to the beautiful reflection reflecting back from the broken mirrors

that are the weary days and weary ways

of this curious existence.

To those when stepping into the absurd spotlight of Society

unapologetically proclaim:


"Though I must play your game,

you will never win."
I thought it right to assess some antidepressants, which philosophers are more inclined to call mood enhancers.
This was during my foray into human enhancement, substances intended to enhance physicality, cognition or mood. Nootropic compounds concern the latter two categories.

The most commonly prescribed mood enhancers are serotonin reuptake inhibitors (SRIs), but it takes over a week for these compounds reach their peak effect.
Thus I approached them with the notion that a limited dosage might point to their character, though not revealing it. These considerations in mind, I set about acquiring a few miscellaneous anti-D's.

Fluoxetine was the first successful selective serotonin re-uptake inhibitor (SSRI), better known by its original brand-name Prozac. Fluoxetine has an acute biological half-life of between 1-3 days. Presence of a trifluoromethyl group on the compound deserves note, I wonder what the presence of electronegative fluorine atoms add to the psychoactive flavor of a compound (subjective effects).
I administered a single dose by mouth, there was some indication of subjective character. Light serotonergic sensations and seemingly benign mood-dampening, there is a ****** towards the positive. Waking headspace relatively uninteresting. Observed hints of oneirogenesis, did not manifest in enough character to be detailed - a sort of vivid, 'pulsive wandering, more pronounced in contrast to its waking character.
Good experiment, interesting results.
Ligand     Ki (nM)   Ki (nM)
Target      Flx            Nflx
SERT        1               19
NET         660           2700
DAT         4180         420
5-HT2A   200           300
5-HT2B    5000         5100
5-HT2C    72.6          91.2
α1             3000         3900
M1            870           1200
M2            2700         4600
M3            1000         760
M4            2900         2600
M5            2700         2200
H1            3250         10000

Sertraline is another popular SSRI, also known by it's original brand-name Zoloft. Sertraline has a variable half-life, on average 26 hours.
It's metabolite, desmethylsertraline, has a half life between 62-104 hours but is a far less potent Serotonin Releasing Agent (SRA).
The presence of two chlorine atoms is interesting. The usual, phenomenal serotonergicity is present and pushing towards the positive.
Some nausea, particularly when hungry (this disappeared after some minestrone soup). Some faintness after physical exertion. This dose did not promote onirogenesis. There was a moment of cognitive distortion when the proportions of a focal object seemed to be growing in-and-out, shifting in size.
Site                 Ki (nM)
SERT              0.15–3.3
NET               420–925
DAT               22–315
5-HT1A       >35,000
5-HT2A          2,207
5-HT2C          2,298
α1A        ­        1900
α1B                 3,500
α1D                 2,500
α2                  477–4,100
D2                  10,700
H1                  24,000
mACh           427–2,100
σ1                   32–57
σ2                   5,297

Escitalopram is an SSRI commonly prescribed for major depression and generalised anxiety. It is the (S)-stereoisomer of citalopram. The biological half-life is of escitalopram is between 27-32 hours.
I administered a dose and thought the phenomenal serotonergicity less apparent than fluoxetine but then gastro-intestinal disturbance was noted, I surmised it has a high affinity for 5-HT2C.
Any oneiric qualities were not readily apparent after a single dose, relatively little visual imagery which is understandable given its lack of affinity for 5-HT2A. I found this to be philosophically interesting. Mood elevation observed in bursts of conversation and as odd sensations, possible mental discomfort.
Ligand,
Recptr     Ki (nM)
SERT       2.5
NET        6,514
5-HT2C   2,531
α1            3,870
M1           1,242
H1           1,973

Venlafaxine is a selective serotonin-norepinephrine reuptake inhibitor (SNRI). Venlafaxine and its metabolites are active for about 11 hours.
Initial subjective effects similar to a very light empathogenic stimulant. Perception of altered attention-span/increased reflexive response; energizing yet paradoxically much yawning.
Ligand,  Vnfx      Dvnfx
Recptr    Ki(nM)  Ki(nM)
SERT  ­    82           40.2
NET       2480        558.4

Tianeptine is a tricyclic antidepressant (TCA) with an unusual mechanism of action. It is an atypical agonist of the μ-opioid receptor and has been described as a (selective) serotonin reuptake enhancer (SRE). It has a short duration as sodium salts [prescribed form] of between 2-4 hours but as sulfate this can be notably extended, some of its metabolites are active for longer than tianeptine itself.
Definitely anxiolytic, quite artificial; possible aphrodisiac. I find its opioid activity dissuading, requires caution.
Site          Ki (nM)
MOR       383–768 (Ki)
                 194 (EC50)
DOR      >10,000 (Ki)
                 37,400 (EC50)
KOR      >10,000 (Ki)
                 100,000 (EC50)
All other transporter/receptor/sub-receptor values are >10,000 (Ki).

Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI) with affinity for some nicotinic receptors. Bupropion and its metabolites are active for between 12-36 hours. Interestingly it is a substituted cathinone.
Initial subjective effects similar to a fairly light stimulant. Perception of increased attention-span and improved cognition. It is an onirogen that is neutral in quality, enhancing vivid dreaming (a boon of its nicotinic affinity which is counteracted if the stimulant component impinges on sleep). Completely absent of serotonergicity, curious.
The N-tert-butyl group's effect is most interesting, how it affects metabolism. I took 150mg ******, as extended and as instant release (the latter was more pronounced). Interesting to compare with other cathinones, and curious to think of other bupropiologues (for example, 3-Methyl-N-tert-butyl-methcathinone). A decent compound, probably useful for a range of things beyond its indication.
                        Bupropion    R,R-Hydroxybuprp­n   Threo-hydrobuprpn
AUC               1                     23.8                                  11.2
Half-life         11 h                 19 h                                 31 h
IC50 (μM)
DAT               0.66                  inactive                          47 (rat)
NET               1.85                   9.9                                  16 (rat)
SERT              inactive          inactive               ­            67 (rat)
α3β4 nic         1.8                   6.5                                   14 (rat)
α4β2 nic         12                     31                                   no data
α1β1γδ nic     7.9                    7.6                                  no data

Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA), its monoamine oxidase inhibition lasts about 8–10 hours and wears off completely by 24 hours. Inhibiting the decomposition of monoamines (e.g. serotonin, norepinephrine and dopamine) increases their accumulation at an extracellular level. It tends to suppress REM sleep and so it lacks oneirogenic properties.
Feeling of well-being, less constrained by the usual anxieties; openness. Relatively unnoticeable side-effects when diet is carefully managed. Made the mistake of eating a cheese and turkey sandwich (i.e. foodstuff rich in tryptophan/tyramine), slight indications of serotonergicity later became apparent when in bed: feelings of overheating and flushing, slight sweating, racing thoughts and anxious discomfort. A reminder of Shulgin's old adage: "there is no casual experiment".
Combination with a select few tryptamines (not 5-MeO-xxT) should be safe and synergistic (perfect for pharmahuasca), but is very dangerous to combine with serotonergic drugs.
Svetoslav Nov 2021
Let the night in, for I'll be writin' the letters of light in the air.
Our bodies pulsate by the notes of gentle symphonies, and we adhere.
Two elements shakin' and mergin' into one.

We are makin' it and cravin' for more of this addictive fun.
The moonlight rays reach the shapes of the furniture, movin' along with the temperature, increasin' with each movement.

Like desert diamonds, we will reflect in the pearly sun.
You will be the meadow that I will prefer and the lover within my arms to cover. Until amusement, let my cries give you inducement.

From the color of sulfate, this night is glowin' with universal sparks.
We both have bewitchin' feels for each other.
I am tastin' honey on the curves of her skin, and we embark on the hill.

The darkness is sailin' on the waves of our unity.
We stomp on a bed full of cherries, and the night stays still.
She feeds me with her tempting body, and I see her lucid thrills.

I climb on her high balconies, and I am one with the moon,
drinkin' from the passion of her milky skin.
Our hearts entwined. I attune from the voice of the raccoon.

Her body is femininity incarnated into a guitar. I play on her strings, listenin' to the music from noon until dawn, bound to our emotional devotion. Our irresistible pleasure is bowing to our connection.
Excerpt from my novel ''Last Occurrence''
Read it here: https://www.amazon.com/dp/B09KF4DYMJ
Svetoslav Nov 2021
Let the night in, for I will write the letters of light in the air.
Our bodies pulsate by the notes of gentle symphonies, and we adhere.
Two elements shakin' and mergin' into one.

We are makin' and cravin' for more of this addictive fun.
The moonlight rays reach the shapes of the furniture, movin' along with the temperature, increasin' with each movement.

From the color of sulfate, this night is glowin' with universal sparks.
We both have bewitchin' feels for each other.
I am tastin' honey on the curves of her skin, and we embark on the hill.

The darkness is sailin' on the waves of our unity.
We stomp on a bed of cherries, and the night stands still.
She feeds me with her tempting body, and I see her lucidly.

I climb on her high balconies, and I am one with the moon,
drinkin' from the passion of her milky skin.
I attune from the voice of the raccoon.

Her body is femininity incarnated into a guitar.
I play on her strings, listenin' to the music from noon until dawn,
bound to our emotional devotion.
Excerpt from my novel ''Last Occurrence''
Read it here: https://www.amazon.com/dp/B09KF4DYMJ
Loveless Wraith Mar 2012
Donuts, o donuts,
Wheat Flour Enriched
Soybean,
Palm and Cottonseed Oil Hydrogenated
Vegetable Oil Partially Hydrogenated
Cocoa Processed with Alkali,
Sodium Acid Pyrophosphate
Sodium Aluminum Phosphate
Aluminum Sulfate
Salt, Dextrose, Soy Lecithin,
Guar Gum, Cellulose Gum, Tapioca Dextrin,
Corn Dextrins, Mono Diglycerides,
Citric Acid, Enzymes,
Natural & Artificial colors & flavors
Sorbic Acid and Sodium Propionate
and Potassium Sorbate
To Retain Freshness:
Eat 'em up yum.
I'm such like a chemical equation.
May evening, 10 pm as the time stitch stick, I was ionized.

We were, perfectly just like Berilium and Sulfate combination did.

Slowly by time, it solved like a combustion struck by appearance of troublesome oxygen and we survived
whereas the beliefs evaporated like the hydrogen dioxide.

In the end, you won over it, finalized the equation by eliminating me both in left and right side.

Leaving me partially ionized, failed thermochemistry as the exothermic spread no waste and the enthalpy was hurt much more.
and without electron I lost.
kt mccurdy Oct 2014
2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]ethylamino] ethanol sulfate

Sulfate- dry collision with salty white plaster, plaster walls, my plaster teeth in the palm of my plaster hand, the same palm you touched nervously with your fingertips, when your translucent skin showed we have the same blue veins, you with no love line. I’ve ran into walls, trees, dead ends, bursts of hail, but worst of all– you

Ethanol- black liquid gas,a nozzle in my car engine, fracked through my exhaust(ion) burn my esophagus like sweet ginger ale gin, double chin. I’m drunk, so I’m seeing double. Re/frac/tion.

Ethylamino- alcohol: a drizzle in a rainstorm, i can’t contain myself, exploding inside a glass bottle. a defective windshield wiper, reprocessing my words: “ethyl and coke tastes like cough syrup”, I say. either or, neither will help me.   ethyl as fuel is not safe to drink
ethyl as alcohol is not safe either. swirled away in a plastic whirl.

Pentyl- discovered in a collision of ultra violet light with argon, noble gas. overdose symptoms include convulsions (check), drowsiness (check), headache (check), difficulty breathing (check), vision problems, (check). But not for the reasons, or for the causes, I’ve listed.

Amino- building blocks to a withered corn husk of my body. 9 essential amino acids. Find them in your grocery store: egg whites, lysine in sunfish, cod, dolphinfish but please, no mercury. Maybe I have 1 left, maybe 2, after each labored breath entrapped by porcelain walls, cool on my forehead, warm on my hands, dampened dew on fingertips with pressure on my skin, sewer raindrops on my nose, now i’m so good (to you) I can upheave my 7 other amino acids on demand. No more dew on this fluorescent skin, I've always been too artificial to be compared to nature

Quinolyl- you are created by the removal of one hydrogen atom. I am created by the induction of two. This is how we are similar: exposed to light, we change. Your ancestry proceeds you, impurity in a chemical science, derivative of quinoline, which is a derivative of coal tar. you are an dye, a resin, parasites feed on your smell. I lust on your parts, **** out your solubility, desecrate your elements. I own you, don’t think you own me.

4- one milligram less than what disintegrates on the tongue's bitter perception, each night

Chloro- back stroke, breast stroke, my favorite is dead man’s float. inflamed skin, cracked elbows, an allergy

7- years since you’ve been with me, although I own you, you do not own me.

4- exponent of the previous, the total sum of pop art pills by night’s end. sometimes I forget.

2**- the number of techno-colored candies in the morning

A body is made up of chemicals
i am grateful for stretch denim on days
when
          **** it
is a fashion statement
for lavender laundry detergent
because that smell reminds me of the home i've built in my head
for tea at
2 a.m.
when all the things i've done race in my head
because the next morning, i usually get my **** together
for colds
because they make eating an entire roll of cinnamon buns
completely justifiable
for the mountains that surround me
for NPR and good, rated M fanfiction
for def poetry when i can't find the right words
for finding a pack of cigarettes when it is only
11:30pm on a thursday night
and i am well past drunk in a slightly damp armchair
for harry potter and neil gaiman
for when twenty dollars fills up my gas tank
for my grandma's potato salad and biscuits with honey
for feminist zines that make me want to smash the patriarchy
for burts bees chapstick and jasmine-green tea
for friends who let me cry on their
bedroom floors
for books that keep me entertained
(even if that means me crying in my bathtub while reading them)
for courtney love and joan jett because those *******
have ridden in my car with me over many
heart-breaks
for well-water and sulfate free red wine
for johnny cash and new orleans and whiskey
for salt-- because that **** can wash away anything
for farmer's markets and co-ops
for bottles of water  and for cookie dough
when my mouth
is the consistency of cotton  and my mind is a little bit gone
for warm days in January and cold days in September
for breakfast and for hikes that begin at five a.m.
for summer nights drunk on wine and a little too much fire
for friends who call me 'momma bear' and for friends that call me 'baby bird'
for poems that give you cold chills
and flowers stolen from my neighbor's yard
for skin that smells like the sun and sage
for beeswax candles
and the smell of clean laundry
for days when i wake up and realize
i could have died on a bathroom floor
AJ Feb 2014
there are certain feelings that have no parallel
moments that can't be replicated
like the last class of the day on a friday
it's chemistry class, and your teacher is speaking in his thick raspy voice and the words flow through you
you recognize that he is talking but you don't take in the meaning
your eyes and mind are focused on the clock
forty minutes forty minutes forty minutes
and the promise of the weekend fills your body to the brim with a hope that cannot be matched

you are sent to the back of the room to do a lab
and your partner is the same scrawny boy with the chestnut eyes and the softest blond hair that you have ever felt
he's lighting the bunsen burner while you fiddle with the fraying elastic on your decade old goggles
he turns to face you and smiles and you note that his smile encompasses his whole face, his brown eyes beaming at you behind the yellow tint of his safety glasses
you smile back at him and the idea of who this boy is begins to sink into your thoughts
this boy is neither friend nor foe
he is potential
he is a boy you never speak to except to copy notes and you realize that depending on a series of choices this boy could be either everything or nothing to you
the thought is overwhelming so you shove it away
right now, you are lab partners
and the simplicity of that makes you grin

there is sunlight pouring into the chemistry room on the west side of the third floor and it dances across the black lab table where you and the boy are fiddling with a test tube of copper sulfate
you do not speak, just work
hands in perfect synchronicity as you adjust the utility clamps and let the burner ignite
it is almost like a dance, a ballet of hands as your fingertips do pirouettes around each other, recording and observing and adjusting and other science class endeavors
there is a certain intimacy that goes with looking into someone's eyes through the glowing orange of fire coming from a secondhand bunsen burner
both of you are buzzing with the energy of friday but neither of you rushes, wanting to gather each detail, to memorize each beat

it goes fast anyways, and soon you are scrubbing a still warm test tube in the sink next to a girl with hair the color of the night sky
you let out a gust of air to dry the glass and the girl's onyx locks flutter in reaction to the newfound breeze
with one more glance at her, you turn and take your seat, tapping your foot to the rhythm of  the clock, and sitting silently next to your lab partner
you watch as his wide eyes dart back and forth across a page of a book as though he is a cat trying to catch a mouse
chasing the poetry and attempting to trap each word in his mouth, exploring the letters with his tongue

he smiles when he sees you watching and you smile back
then lean into your desk, close your eyes, and capture the moment
Em Glass Sep 2018
The skin on my fingertips is cracking.
I washed all the dishes by hand.
I dried them and stacked them
and put them away.
I walk on the wall between honest and kind.
I wait for the film to unwind,
or become exposed.
The darkroom is where I first
taught my heart to close.
To add the sulfate and turn on the bulb
so the picture wouldn't change,
the way turning on the light
doesn't knock over the first domino.
How your arms rise from your sides
when you skip, a bird taking flight.
How you lie on your stomach
to photograph a seagull.
How do you love two people?
When I close one part,
the cracks form somewhere else.
I walk on the wall between honest and kind.
It is seven feet tall.
I throw an arm out to either side for balance
but it reminds me of you,
so I fall to the right.
precarious
z  Feb 2016
Nacho Supreme
z Feb 2016
enriched macaroni product
(wheat flour, glyceryl, mono
stearate, niacin, ferrous sulfate
(iron),
thiamin mononitrate (vitamin b1)
riboflavin vitamin b2 folic acid)
cheese sauce mix (whey, malto
dextrin, corn syrup solids salt palm
oil modified food starch milk
fat milk protein concentrate con
tains less than 2% of tomatoes
milk mediumchaintriglycerides sodium
tripolyphosphatecream citricacidsodiumphosphatelacticacid naturalflavour
* onions* tricalciumphosphatepartiallyhydrog
enatedsoybeanandcottonseedoil guargum monosodiumglutamate garlic**
yellow5yellow6spicemalicacid enzymes disodiumguanylatedisodiuminosinate artificialflavour cheeseculturemodifiedfoodstarchmaltodextrinpotassiumchlorideacety­latedmonoglyceridessaltmediumchaintriglyceridesapocarotenal(colou­r)contains;
wheat
milk
48(Cd)
is a highly toxic, poisonous and soft metal used in many production processes, but mainly mixed with Sulfate to make the color yellow.

metal is suppose to be tough.
Not malleable, ductile and easily cut.
Polished to a lustrous finish but will corrode in due time.

I am Cadmium;
soft and easily cut, my finish does not last, I can be poisonous if you don't filter me.
But if you mix me correctly, I am a beautiful Yellow.
Gabrielle  Jun 2024
Salt Mines
Gabrielle Jun 2024
My sad is copper sulfate,
A blue shriek in my sternum,

A pressure frame inside me,
Too far away to burn him.

Leave my sad to crystallise,
Please just keep your distance.

Through my stalagmites of sorrow
Take the line of least resistance.

I carve companions from the rock,
Each one a salty clone.

I’ve made societies down here
To sit with my alone.

— The End —